Although in vivo evaluation is pivotal for preclinical development, a rapid in vitro quantitative screening method is mandatory for the first round determination of potential anti-fibrotic compounds, since any animal model represents the same complexity as a human and unclear in vitro data will unlikely be cleared in vivo.
There was no concentration-response relationship reported in one study and unclear in three other studies.
The Pentagon often relies on information from warlords and other Afghans whose loyalties are unclear in a country riven by decades of war and tribal rivalries.
3 Moreover, the way the trials handled missing participant data varied and was unclear in about a fifth of reports.
However, we encountered many instances of incomplete, ambiguous, and unclear documentation in the chart documents in a manner that appears to have been experienced by other researchers who have tried to document antibiotic timing[ 3, 4, 8, 9, 13, 15, 19, 20].
Although norgestimate had been on the market from 1995, other studies either did not consider norgestimate or were underpowered (for norgestimate, only five exposed cases in the Dutch study, 9 15 in the CPRD study, 4 and an unclear number in a German study with lower total numbers 13).
"Careless", "insincere" and "unclear" communication has fuelled a surge in complaints against the NHS in England, the health service ombudsman has said.
We do not expect it to be a major bias of the study: the reading of the set was rather fast, as in current screening practice, and even if some images could be recalled, recalling does not imply a change in accuracy, and it is unclear in which direction such a bias, if any, could go.
Opinion, for Plato, was a form of apprehension that was shifting and unclear, similar to seeing things in a dream or only through their shadows; its objects were correspondingly unstable.
The strength and direction of the associations between inflammation and coagulation biomarkers with kidney disease onset and progression remain unclear, especially in a population-based setting.
