Sentence examples for and to the rationale from inspiring English sources

These findings may be helpful in the development of AMP as a chemotherapeutic drug for breast cancer, and to the rationale for enhancing its anti-breast cancer efficacy by inhibiting protective autophagy.

The isolation of this strain, which is pathogenic, but lacks the QS-regulator LasR and its cognate autoinducer 3O-C12-HSL, constitutes a challenge to the current model for explaining the mechanism of P. aeruginosa virulence, and to the rationale for searching compounds that inhibit LasR activity as a means to treat infections caused by this bacterium [ 33].

Such schemas may vary from the three dimensional structure of an organ, to the complex function of (a component of) an organ, to a certain reaction pattern characteristic to a group of diseases, and, to the rationale of a diagnostic or therapeutic intervention.

The objectives of this paper are to provide an introduction to meta-analysis and systematic review and to discuss the rationale for this type of research and other general considerations.

Objective: To provide a review of the humoral and cellular immunology of endometriosis and to discuss the rationale for future approaches to diagnosis and treatment.

The aim of this study was to analyze and describe cases of ovarian cancer in pregnant women treated at our center and to review the literature concerned, and to discuss the rationale for therapy.

Thus, our study promises to significantly advance our understanding of the pathogenic mechanisms that lead to muscular dystrophy and to provide the rationale for pharmacological treatment of DMD patients.

However, further research is required to substantiate these speculations and to explore the rationale for dispensing all inpatient medication as OSD supplies, even for inpatient medication which is extremely unlikely to be continued at discharge.

Our aims were to evaluate the tolerability, clinical outcome and to establish the rationale for using capecitabine in combination therapy as an alternative to infusional 5FU in NETs.

The items included in the module prompted physicians to risk-stratify adult syncope patients based on EKG findings, and to explain the rationale for head CT and admission.

A review on in vitro preclinical tests used to evaluate the effects of drug combinations and to design the rationale of combined chemotherapy protocols is presented.