The phrase "and thorough change in" is correct and usable in written English.
It can be used when discussing a significant or comprehensive transformation in a particular area or aspect.
Example: "The organization is undergoing a thorough change in its management structure to improve efficiency."
Alternatives: "and complete transformation in" or "and significant shift in".
Metamorphosis entails an abrupt and thorough change in an animal's physiology and biochemistry, with concomitant structural and behavioral modifications.
"We are not allowed to exercise the fundamental rights given to us in the Constitution," he said in May in announcing the formation of a new party, the Reform Party, whose objective, he said, was "a complete and thorough change in the way this country is run".
Contamination effects were observed both visually in the field and thorough changes in the spectral reflectance patterns of vegetation.
But the speed of it, the constant and thorough changes in dynamics within open, mobile harmonies, and, in particular, the inventiveness of Mr. Harland, intimated the heat and light of free improvisation.
The answer why not, I fear, is that Labour is too executive-minded, too fearful of investing in parliament as an institution and too fearful of thorough change in the governing system – despite the way it is being subverted and shrunk by the Cameron government.
(2) If more than 5%% of spare parts stock out of the total amount of equipments cannot meet the operational needs during the guarantee period of quality, it indicates that the manufacturing facility has existing flaw in the design of the equipment which leads to the high fault rate and therefore needs to implement thorough change in design.
The ECM composition of the FGF2-treated fibroblasts favors the pro-regenerative outcome in the wound site directly by affecting the balance between scar formation and tissue regeneration and potentially thorough changes in cell attachment to ECM, cell migration, and cell proliferation.
An admitted perfectionist, Ueda felt that only one or two out of 500 artists who applied to work on Shadow of the Colossus met his criteria, and often demanded thorough changes in design until it matched his vision.
Richard A. Boucher, the State Department spokesman, said Tuesday that "reaching a political settlement will require some fairly thorough changes in the way Haiti is governed, and how the security situation is maintained".
Asked whether the administration had a position on whether Mr. Aristide should finish out his term, which ends in 2006, he said, "We recognize that reaching a political settlement will require some fairly thorough changes in the way Haiti is governed and how the security situation is maintained".
It was forwarded to Washington and Arab capitals on Monday, in anticipation that Mr. Bush would call for thorough changes in Palestinian governance.
