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Ethiopia, Africa's second most populous country, is overwhelmingly rural and this has hampered the expansion of formal healthcare services and infrastructure.
However, clinical trials have revealed high systemic toxicity and this has hampered its utilization as an anti-cancer agent.
However, methanol is very much more difficult to oxidise anodically than hydrogen, the more conventional anode fuel, and this has hampered development of commercial direct methanol fuel cells.
However, most FPs lose fluorescence at a pH lower than their neutral pKa (∼6), and this has hampered their application in acidic organelles (pH ∼4.5 6.0).
To date, few S/MARs have been identified and this has hampered efforts to develop meaningful biological models.
Cultivated peanut has a very narrow genetic base and this has hampered the progress of genetic studies using cultivated × cultivated crosses.
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Studies conducted so far on tumor samples and normal tissues rely on the use of commercially and non-commercially available antibodies recognizing both α-enolase and MBP-1, this has hampered the possibility to clearly evaluate the relative expression of the two proteins by immunohistochemistry.
Pre-eclampsia is a heterogeneous condition with respect to the onset and severity of the clinical manifestations, this has hampered the development of screening strategies and the development and assessment of potential preventive interventions.
This has hampered sequencing, assembly, identification, and application of Y-chromosomal markers (Greminger et al. 2010).
In turn, this has hampered past attempts to understand how, and which, intervention characteristics relate to clinical outcomes.
This has hampered our military efforts; contributed to American, coalition and Afghan deaths; and helped sour relations between Kabul and Washington.
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