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Cartilage degradation and subchondral bone changes were pronounced in the medial side of tibiae, and these progressed with age and correlated positively with chondrocyte apoptosis.

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However, pre-malignant lesions may be present in a high proportion of healthy individuals, and whether these progress to an invasive metastatic fatal cancer can depend on an extraordinarily complex interacting network of errors, imbalances and disturbances.

These progress and development are attributed to digital electronic technology and digital memory evolution.

With the metabolic pertubations associated with a Western lifestyle however these progress and become clinically evident (Fig.  5b).

Approximately 70% of tumours are superficial at initial diagnosis, but of those about 60% recur and 10 20% of these progress (Ro et al, 1992).

Each of the 38 chapters covers one analysis topic, and these topics progress from simple to advanced.

If well-timed activation waves reverberate in the circuit and these waves progress with constant speed, it is possible to store information about two or more instantiations of a given engram (Hayon et al. 2005).

In a non-familial population, it is estimated that the average adult pancreas has five PanINs and that 0.86% of these progress to invasive cancer.

Of these subjects, 17 progressed to dementia, and 15 of these progressed to dementia of the Alzheimer type (DAT).

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