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To further improve the transfer characteristics, plasma hydrogenation or a polymer coating that can passivate surface defects and therefore restore the intrinsic properties [16] should be implemented.
A possible solution to this problem may be long-term culture of the HIVRT in lymphocytes to introduce compensatory mutations and therefore restore virus infectivity.
With epigenetic editing technology, one could attempt to reprogram these disease-promoting epigenetic states and therefore restore normal functioning of the cell.
This ruled out the possibility that actin cytoskeleton changes in Ect2-depletion indirectly decrease membrane tension and therefore restore CME in mitotic cells.
This provides a strong rationale for novel leukemia therapeutics that target inhibitory molecules to reverse exhaustion and therefore restore T-cell function and enhance GVL activity.
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Image deconvolution is a useful tool to more unequivocally address the localization of a molecule in a small compartment as this procedure eliminates the contribution of optical diffraction and therefore restores the "real" image from the acquired samples [9].
GA acts as a potent inhibitor of these cells and therefore restores MBD-1 levels.
The presence of the ctrA(T170A ), sciP(T24I ), or sciP T65A ) alleles (ctrA * or sciP *) restores the synthesis of the factor X in the Δ mucR1/2 mutant background, and therefore restores HvyA synthesis and WT buoyancy.
In contrast, transient expression of glypican-1, although heparan sulfate-modified — and therefore restoring heparan sulfate expression in cells with syndecan knockdown — was unable to rescue the effect of heparanase on exosomal syntenin-1 and CD63.
The maintenance of CD4+ T-cells and CD8+ T-cells numbers characterizes the efficacy of HAART [ 22– 24], which inhibits viral replication, slows the progression of immunodeficiency, and therefore restores immunity, increasing the quality of life of HIV-1-infected individuals.
We thus propose that abnormalities in β1-ADR signaling in the APP mice are responsible for their deficit in social recognition, and therefore restoring the function of the β1-ADR in APP mice would rescue the social recognition deficit.
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