The phrase "and therefore largely" is correct and usable in written English.
It can be used to indicate a conclusion or result that is primarily due to a preceding statement or condition.
Example: "The project was a success, and therefore largely attributed to the team's hard work and dedication."
Alternatives: "and thus mainly" or "and consequently primarily".
But its rules are merely advisory, and therefore largely ineffective.
A man's conduct is considered inevitable and therefore largely innocent, but a woman's thought-out and reprehensible.
His arms and legs may have been crafted from steel and circuitry, but the rest of him was Lee Majors, and therefore largely made of wood.
The Arabic alphabet consists of only 29 letters, and its spelling is 95% phonetic and therefore largely self-explanatory – something that could never be said for English.
Although league tables for secondary schools are still published annually by newspapers north of the border, the Scottish Executive remains firmly opposed to them, arguing that comparisons are not like-for-like and therefore largely meaningless.
Yuval Levin has one of the most perceptive takes on Charles Murray's "Coming Apart" that I've read to date: … the cultural disaster Murray describes seems to be a failing of America's moral (and therefore largely its religious) institutions.
Although several normal tissues such as liver, spleen, colon and bone marrow contain high activities of βG, this enzyme is located in lysosomes (Price and Dance, 1967) and is therefore largely inaccessible to highly hydrophilic glucuronides which pass poorly through the cell membrane (Haisma et al, 1992).
Discography is currently the main diagnostic modality for DLBP; however, its reliability is controversial because discographic results rely heavily on the reproduction of the patient's pain and the operator's judgment and is therefore largely influenced by subjective factors.
Known as The Belleville Three, Atkins, Saunderson and May pretty much invented modern dance music and are therefore largely responsible for every nuanced sub-genre that's shone in the clubs since.
Barclays' Richard Taylor said: We estimate that these divisions currently generate earnings before interest and tax of just £4m (around 3% of group earnings), and are therefore largely ignored by investors.
