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This complex is necessary to connect ubiquitin to the substrate that is bound to the F-box protein and therefore directs it to protein degradation at the 26S proteasome [ 56].
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As for "moneybags Roman", the fans knew he'd brought the club success on a previously unimaginable scale and therefore directed all their anger at the managers he appointed rather than his royal self.
During this period, sociology was concerned with practical problems of agrarian inequality and poverty and therefore directed to "solve social problems through reformism and social adjustments" (Cheng and So 1983, p. 475).
Indeed, appearance of HAMA could potentially also induce anti-HAMA antibodies, which could in turn be anti-idiotype antibodies and therefore directed against CD20.
Our results illustrate the dynamic process by which key transcription factors regulate enhancer formation and, therefore, direct future gene expression to achieve mononuclear phagocyte development.
These ships differ from traditional oil tankers by their unusual form and therefore direct hydrodynamic analysis is used to determine design vertical wave bending moments instead of adopting IACS rule values.
But what's also now possible is that an individual can start one of these groups, be the sole funder and therefore direct in which race -- or races -- he or she wants to intervene.
However other EGFR core proteins and Notch pathway members showed no elevation of mRNA expression in the corresponding transcriptomal class and therefore direct correlation could not be established.
In vitro genomic selection with transcription factors differs from other affinity-based strategies because it uses the native genomic background, and therefore direct transcription factor targets are identified without influences from complex cellular environments [37].
Generally, long-term data on individual trees and therefore direct age estimates are lacking.
A possible explanation is the difference in methodology, and therefore direct comparisons of our results with theirs are difficult.
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