Sentence examples for and thereby subsequent from inspiring English sources

We did, however, observe that in A375 R1 tumors, vermurafenib provoked the MAPK pathway via compensatory increases in c-RAF and Ksr; this likely lead to induction of Hif-1α and Sp1 transcription factors (independent of c-Myc), resulting in increased levels of hexokinase II, membrane GLUT-1 and, thereby, subsequent FDG uptake [39, 40] (Figures 3B 4B and 5; Additional file 6: Figure S6).

The use of biocidal masks may significantly reduce the risk of hand or environmental contamination, and thereby subsequent infection, due to improper handling and disposal of the masks.

The gastric content is a major factor in pathogenesis of GERD and lycopene was observed to have marked effect on that through decrease in acidity (total and free), gastric volume and thereby subsequent increase in pH.

Thus, observed increase of platinum intracellular accumulation stimulated by E-4IB pretreatments could be explained by a decrease of GSH availability to form cisplatin conjugates and thereby subsequent reduction of cellular efflux of the drug.

Through the use of these tools, the pastoralist has learned how to manipulate his/her flock (or herd) to graze or avoid certain patches of vegetation and thereby effect subsequent changes in land cover over time.

Our results suggest that R50E could not bring αvβ3 to FGFR due to defective integrin-FGF interaction, and thereby disrupted subsequent signaling steps.

The serum might have helped primarily in better cell adhesion to the dish and thereby promoting subsequent neural differentiation in KO medium.

However, recycling of CXCR7 was markedly attenuated, suggesting that lowering the pH in the lumen of the endosome is required for the dissociation of CXCL12 from CXCR7 and thereby promoting subsequent receptor recycling to the plasma membrane.

If perfusion pressure is too high, coronaries may rupture and, thereby, impair subsequent dye perfusion.

For instance, the selective inhibition of necrosis or apoptotic cell death may defend inflammation and thereby reduce subsequent tissue damage.

42 Future research should examine other environmental and lifestyle risk factors that could chronically stimulate the parathyroid gland and thereby affect subsequent development of primary hyperparathyroidism.