Sentence examples for and thereby regulating from inspiring English sources

Three possible methods of regulating migration by MRP are the direct regulation of the cytoskeleton through actin, sequestration of PIP2 and thereby regulating PKC mediated cell migration and lastly, functioning as a reserve for Ca2+/CaM and therefore regulating its control of migration [7], [8].

Drugs affect blood vessels by altering the state of contraction of the smooth muscle in the vessel wall, altering its diameter and thereby regulating the volume of blood flow.

Heparanase accomplishes this by degrading HS and thereby regulating the bioavailability of heparin-binding proteins; priming the tumor microenvironment; mediating tumor host crosstalk; and inducing gene transcription, signaling pathways, exosome formation, and autophagy that together promote tumor cell performance and chemoresistance.

Due to their capability of modifying chromatin structure and thereby regulating gene transcription, histone deacetylases (HDACs) have been reported to play important roles in osteogenesis and considered a promising potential therapeutic target for bone diseases, including osteoporosis.

In A549 lung cancer cells, IRP2 can regulate the expression of TfR1 and ferritin by changing its own gene expression, and thereby regulating iron metabolism (Cheng et al., 2014).

Thus, it is likely that the balance between intracellular amounts of HES1 and LMO3/HEN2 might determine expression levels of Mash1, and thereby regulating neuroblastoma cell growth.

These studies showed that CDC and CDKs participate in the regulation of cellular cycle directly and thereby regulate cell size and cell number.

Thus, high CA levels inhibit TH activity and thereby regulate its own intracellular concentrations via feedback regulation.

HDACs form complexes with and thereby regulate the activity of members of the E2F family of transcription factors, important regulators of cell cycle progression and proliferation [31] [33].

After its activation, it can activate transcription of various genes and thereby regulate inflammation.

The other class involves genes whose products participate in the epigenetic machinery and thereby regulate the expression of other genes.