Sentence examples for and thereby define from inspiring English sources

Bromodomain and extraterminal domain (BET) proteins act as cellular cofactors that tether the murine leukemia virus (MLV) pre-integration complex to host chromatin via interaction with the MLV integrase (IN) and thereby define the typical gammaretroviral integration distribution.

Moreover, this strategy could be extended to other CDPKs to identify their substrates and thereby define the pathways they control.

Covalent histone modifications can alter chromatin structure and thereby define transcriptionally active or inactive chromatin states [ 29].

Therefore, the lack of resources and the generally poor health care systems may limit (and thereby define) what is actionable in WGES findings.

Every newly diagnosed mCRC patient should receive at least a short course of systemic chemotherapy (e.g. two months) to estimate his/her aggressiveness of disease and thereby define the right surgical candidate (the responding patient).

38, 39 Receptor biomarkers indicating an enhanced potential for the development of central nervous system metastases may be identified in the primary tumor cell and thereby define future therapeutic targets.

Barack Obama is a great orator, but he is the worst president I've ever seen when it comes to explaining his achievements, putting them in context, connecting with people on a gut level through repetition and thereby defining how the public views an issue.

Dendritic structure critically determines the electrical properties of neurons and, thereby, defines the fundamental process of input-to-output conversion.

On the other hand, its chemical characteristics lead to strong oxidizing properties, capable of damaging any biological molecule [1], and thereby defining the paradigm of oxygen toxicity.

This is accomplished by investigating the spatial correlations in the transforming system via the calculation of several non-equilibrium,n-point correlation functions and thereby defining associated transformation fractions and correlation lengths.

Using genome-wide phylogenetic footprinting, we delineated the location, distribution, and evolution of AIY-specific cis-regulatory elements throughout the genome and thereby defined a large battery of AIY-expressed genes, all of which represent direct Paired/LIM homeodomain target genes.