In fact, several studies have been carried out in recent years targeting both the adaptive and the innate immune system, the majority of which did not achieve their primary endpoint, being often divergent from successful clinical experience and thereby committing physician to off-label use of targeted therapies in face of refractory SLE manifestations.
Prosecutors said Howard's sentence was enhanced because Howard chose his victims based on their religion and "thereby committing a hate crime".
Core promoter-bound Myc Max complexes would then co-ordinately up-regulate the ribosome biogenesis regulon and thereby commit to cell growth and/or proliferation.
This indicates that promoter methylation of specific genes involved in cellular differentiation may occur and thereby commit cells towards a specific lineage.
30 Adenoviruses followed the opposite evolutionary route, losing the integrase gene together with the integration/transposition ability (Fig. 2) and thereby committing to a strictly viral reproduction strategy.
For accepting something like 'According to PW there are worlds where there are blue swans' seems to commit one to PW, and PW is a theory, and so one seems thereby committed to theories.
However, joint commitments thus specified imply a normative relationship between the parties thereby committed: if A and B are jointly committed in some way, then each of them is obligated to act accordingly and each of them is entitled to demand the other's conforming action; in other words, they owe each other such action (cf. Gilbert 2009).
It is easy to construct pairs of sentences X, Y that lead many people to ascribe higher probability to the conjunction X-and-Y than to the conjuncts X, Y. Whether an error is thereby committed depends on reasoners' interpretation of the expressions "probability" and "and".
"The breach of contract which the Trust thereby committed was serious and repudiatory".
By adopting a paraconsistent logic, a dialetheist can countenance some contradictions without being thereby committed to countenancing everything and, in particular, all contradictions.
