Sentence examples for and then activation of from inspiring English sources

And then, activation of TLRs signaling induces specific biological responses against malaria parasites invasion.

The sequential molecular events caused by pathogens were perception of PAMP by PRR, and then activation of the MAPK cascade followed the activation of WRKY-type transcription and R gene.

During slow-fast AVNRT, there is antegrade conduction of the action potential along the slow pathway, retrograde conduction along the fast pathway, and then activation of the atrial muscle, after which there can be further cycles of reentry (online supplement Figures 1A and 1B and related text).

As TRAF2 set a critical barrier for cell apoptosis commitment by tagging activated caspase-8 with a K48-ubiquitin shutoff timer, TRAF2 downmodulation could lower the signal threshold for apoptosis, and then activation (via cleavage) of caspase-3, a downstream effector of caspase-8, was increased in cells with RNASET2 overexpression.

Since Drd1 activation also increases dSPN excitability, which in turn may increase recurrent corticostriatal glutamatergic transmission onto SPNs by altering cortical activity (Oldenburg and Sabatini, 2015), then activation of this receptor alone in vivo will (1) activate PKA and (2) enhance glutamate release.

Then activation of Snail and Serpent, among transcriptional repressors down regulates genes encoding for E-cadherin, claudin and occludin [18-20] [18-20]

Then, activation of AKT and ERK1/2 were examined, evidencing a recovery of AKT phosphorylation and an increase in ERK1/2 phosphorylation in TGF- β-treated Cav1−/− when expression of Cav1 was restored.

These results suggested that if bradykinin receptor phosphorylation leads to IKK2 activation, then activation of G αq, β1 γ2, PI3K and Akt is required.

If no immediate improvement is seen, then activation of Emergency Medical Services by calling 911 is warranted.

Since then, activation of p53 in tumor cells has been the prime focus of cancer drug discovery.

Other works [ 32, 33] also support this revision, revealing that Clb2 and Mcm1 make positive feedbacks; Mcm1 is activated by the low level activation of Clb2, and then the activation of Mcm1 causes Clb2 to be activated at a higher level of concentration in return.