There are two reasons: First, multi-threshold calculation is not always credible [9], and second, when the background is complicated with modulation levels distributed in both the second cluster and the third cluster, background segmentation based on pure modulation is prone to error.
The first cluster comprised 94 subjects from 17 families, the second cluster 50 subjects from 12 families, and the third cluster 115 and 25.
The first cluster had 48 metastatic samples out of 103 (47%), the second cluster had 27 metastatic samples out of 99 (27%), and the third cluster had eight metastatic clusters out of 58 (14%).
The first cluster contains Schledehausen sequences only, the second cluster consists of Bramsche Tower and Bramsche Varus, and the third cluster is a composite of all sequences from Astrup and Ellerbeck.
The first cluster of five patients had disease onset from April 29 through May 1; the second cluster of 14 cases began on May 4, and the third cluster of 12 cases began on May 11 , 2003
One cluster contained widely and strongly expressed genes including OSK1, OSK8, OSK20 and OSK24, a second cluster contained moderately expressed genes and the third cluster contained weakly expressed genes (Fig. 3; Supplementary Table S2).
The first cluster (southern lineage) was comprised of two populations from the southern subregion (DL and ZD), the second cluster (eastern lineage) consisted of the five eastern populations (WX, QL, HB, BC and YA), and the third cluster (northern lineage) included the three northern populations (CD, MK and RT).
The SoA is recursive and the last and the first clusters are adjacent by default, so another II is needed at the last.
Using protective equipment may account for the absence of cases among healthcare workers during the first and the second clusters of SARS in the ER.
