Sentence examples for and the subsequent progression from inspiring English sources

Steatohepatitis may lead to fibrosis and the subsequent progression to cirrhosis.

The development of effective therapeutics designed to target melanoma requires a comprehensive understanding of the underlying biochemical and genetic processes contributing to melanocytic neoplasic transformation and the subsequent progression to an advanced melanoma disease stage.

Loss of filaggrin function seems to play a role both in the pathogenesis of eczema and the subsequent progression of atopy.

The molecular mechanisms of the initial malignant transformation into a CIS cell, and the subsequent progression into overt tumours remains largely unknown.

Persistence of these types is a necessary factor for the development of SIL and the subsequent progression to cancer (Nobbenhuis et al, 1999; Walboomers et al, 1999).

The presentation of HIV antigens by HLA-Bw4 alleles might relieve the inhibition of NK activity, resulting in enhanced lysis of infected cells by NK cells, which could thereby influence HIV viremia and the subsequent progression towards AIDS[ 28- 30].

DeFronzo noted that the natural history of type 2 diabetes involves a reduction in insulin sensitivity during the progression from lean to obese with normal tolerance, and that the subsequent progression to impaired glucose tolerance (IGT) is associated with a further decrease in insulin sensitivity and a relative deficiency in insulin secretory function.

This paper provides an overview of these cellular protein partners of HR-E6, the motifs known to mediate oncoprotein binding, and the agents that have the potential to interfere with E6 expression and activity and thus prevent the subsequent progression to oncogenesis.

The concern arises as to whether the results on the associations between certain factors, in particular genetic variants, and onset or the subsequent progression of breast cancer may be still too preliminary or costly to be applied to population-based screening.

This indicates that the early recruitment of NK and CD8+ cells in DA rats was not sufficient to control the infection and could contribute to the subsequent progression to HSE.

The subsequent progression and response to treatments in all patients were consistent with MFC.