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Intron loss is observed on two occasions: once between two subfamilies of eudicots and monocot and in the second instance, when dicot and moss XIPs diverged from fungi.
The $252 million man slipped and fell in the first instance, then fell on his face in the second instance when a cleat on his right shoe got caught in the shoelace of his left shoe.
Interestingly, in the second instance, when we codon-harmonized the first thirty codons at the 5′-end of the ORF, we saw another dramatic improvement in expression levels (Fig. 1, lane 2, and Fig. 2C).
In the light of the foregoing, our question is whether the state or the Federal Government has the paramount right and power to determine in the first instance when, how, and by what agencies, foreign or domestic, the oil and other resources of the soil of the marginal sea, known or hereafter discovered may be exploited.
But the most complex and most publicly contentious intersection between a risk factor and cancer often occurs in the third instance, when a common exposure is associated with a rare form of cancer.
In the first instance, when all avenues of discussion and compromise have failed, enhanced cooperation should be used more frequently in the field of taxation (such as for establishment of a CCCTB or a financial transaction tax) since harmonised frameworks for taxation will enhance budgetary policy integration.
Fever clearance time was defined as the time from the start of appropriate antibiotic therapy to the first instance, when oral temperature fell to 37.5°C and remained below that level continuously for 48 hours.
"The family has been basically locked out of seeing the young lad, at the first instance when he was at the hospital," he told ABC radio.
We attribute the other 0.2% of results to anomalies such as transient network errors that may have wrongly rendered the web host inaccessible in the first instance when the host was not intended to be blocked.
Ryan Mania's life has been turned upside down since Aintree – literally so, in the first instance, when he was airlifted to hospital after taking a fall from his very next mount, at Hexham the following day.
In the first instance, when industrial capitalism was being born, it came of age by ingesting what was valuable embedded in pre-capitalist forms of life and labor, including land, animals, human muscle power, tools and talents, know-how, and the ways of organizing and distributing what got produced.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com