PDK participated in the design of the study, assisted in the development, optimisation and implementation of the qPCR assays, and helped draft the manuscript.
DLK assisted in the development, optimisation and implementation of the qPCR assays, and helped draft the manuscript.
The high dimension of Raman spectral space (each Raman spectrum ranging from 800 to 1800 cm−1 with a set of 544 intensities) will result in computational complexity and inefficiency in optimisation and implementation of the LDA algorithms.
The system development consists of three stages: namely, metal flow simulation, die failure analysis and design optimisation, and the development and implementation of a machining code.
Fine-tuning of the two-wavelength methodology on a number of technical simulation samples and real fragments allowed its optimisation and implementation to the cleaning needs of Athens Acropolis sculptures where it has been operating for the past twelve years.
The methodology proposed in this research is validated through the development and implementation of a case study involving the optimisation of wing design concepts at an Aerospace manufacturer.
The objectives of such investigations include optimisation of planning processes, stimulation of remuneration systems, optimisation of employment and implementation of standards for machine utilisation (Kanawaty 1992).
In the current article we present the development and implementation of the intervention, structured in three phases: Phase 0 (theoretical underpinning), Phase 1 (modelling of the i-PE pathway - March 2009 to February 2010) and the pilot phase (Phase 2) which includes the initial period of implementation, testing and real-time refinement and optimisation (March 2010 to September 2011).
Several optimisation and implementation considerations are discussed which improve real case usage.
Important future challenges surrounding system optimisation include standardisation of data so that these can be aggregated across systems for meaningful secondary uses, and implementation of data exchange with organisations outside the hospital.
This comparison revealed issues that limited quantification and implementation of design intent and highlighted factors that constrained system optimisation.
