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One was a merchant, the other a banker; and the initial cause of dispute was a refusal of credit.
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Mutations in the genes encoding components of the UPS are linked to neurodegeneration, suggesting that protein aggregation is a result of these abnormalities and not the initial cause of toxicity.
The authors proposed that mutant HTT binding could alter DNA structure or sterically block access by other transcription factors and therefore be the initial cause of HD transcriptional dysregulation.
In LOAD, accumulation of toxic Aβ and p-tau may not be the initial cause of neural degeneration and may instead be consequences of other causative factors5,6.
Vascular damage induced by hypertension may be the initial cause of ICH and BBB dysfunction (with associated edema and leukocyte extravasation) is a secondary consequence [ 55].
Vascular disruption is the initial cause of ICH and blood brain barrier (BBB) dysfunction (with associated edema and leukocyte extravasation) is a secondary consequence [ 5].
When Mojo fades, the initial cause is often failure to accept what is -- and get on with life.
The mechanisms of change and deterioration to chronic state may be as difficult to assess retrospectively as the initial cause of lower back pain [ 2].
Inflammation is a response to eliminate the initial cause of cellular injury as well as the necrotic cells and tissues that result from the original insult.
But the initial cause of the protests was economic.
The initial cause of the protests were austerity measures, such as increased food and fuel prices.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com