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Penalties would generally take the form of the "moral sanction"—the broadcasting of the shame and disgrace of conduct, and the imputation of the reputation of the person responsible (1983b,35 39; 1989, 283).
This allows us to take into account the uncertainty in phase reconstruction and the imputation of missing data.
The presence of recombination influences the accuracy of haplotype phasing and the imputation of missing genotypes.
This will likely include the DNA sequencing of individual animals [ 51], such as widely-used AI sires, and the imputation of sequences.
For a detailed description of the questionnaire, the operationalization of the constructs of the ASE-model, the construction of measurements, and the imputation of missing values we refer to Steenbeek et al. [ 27].
These methods are preferable to simple mean imputation, or simple "best-worst" or "worst-worst" imputation, because the categorization of patients into clinically meaningful subgroups, and the imputation of their missing data by appropriately different models, accords well with best clinical judgment concerning the likely outcomes of the dropouts, and therefore will enhance the trial's results".
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Only a few patients (16/205, 8%) were lost to follow-up and required the imputation of missing data.
Daily measurements of sulfur dioxide and nitrogen oxides were conducted year-round and were used in the imputation of PM2.5 and PAHs for nonsampled days.
A combined reference set comprising 1000G and GoNL improved the imputation of rare variants even further.
The fourth and last step is the imputation of plausible values.
The computation of the standard errors for the estimates presented in this section needs to take into account both the differences in the sampling frames across countries and the variation induced by the imputation of the ability scores.
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