In all cases, the addition of SERF1a decreased the initial lag phase of amyloid growth and accelerated the half time of conversion, thus favoring the generation of ThT-reactive species.
Dose-dependency and non-linear dynamics of TP after single-dose (2, 6 and 18 mg kg−1, respectively) were found, and the half-time of TP was proved to reach 1.3 2.8 h.
In vivo maximum rates of rise and fall of left ventricular pressure decreased, and the half-time of isovolumic relaxation increased, with hcTnT(1) expression.
As indicated in Table 2 and Fig. 2, both of them showed acceptable PK profiles with the areas under the curve (AUCs) of 1.58 and 2.36 μM·h and the half-times of 4.69 h and 3.39 h respectively, indicating reasonable stabilities in vivo.
The relaxatory response was reduced and the half-time of relaxation for CCh was slower in knockout mice, whereas the relaxatory response to SNAP (and the half-time of relaxation) was unaltered.
The intensity was plotted as a function of time and the half-time of recovery, t 1/2, was extracted.
VPA reaches peak levels in mouse serum about 30 min after a single ip injection, and the half-time of VPA clearance from mouse serum is about 1 hr (Nau et al. 1991).
Comparisons of the averaged Ba2+ entry traces and the half-times of the rises in the intracellular [Ba2+] show that the rate of Ba2+ entry is significantly enhanced in Bcl-2 KO cells as compared to WT cells.
However, tissue rOEF during exercise in subjects with FM was significantly lower than in healthy controls, and the half-times of oxygenation recovery (Δ[HbO2] and Δ[Hb]) were significantly longer following fatiguing exercise and cuff occlusion.
However, we observed that rOEF during exercise in subjects with FM were significantly lower than those in healthy controls (see Figure 3), and the half-times of oxygenation recovery (Δ[HbO2] and Δ[Hb]) were significantly longer (see Figure 5 and Figure 7).
Carey performed the song at the 33rd annual American Music Awards, and during the half-time of the Thanksgiving game between the Detroit Lions and the Atlanta Falcons.
