Sentence examples for and the downregulation of from inspiring English sources

Suggestions(5)

and resultant downregulation of

and the amelioration of

and the depression of

and the diminishment of

and the decrease of

The phrase "and the downregulation of" is correct and usable in written English.
It can be used in scientific or medical contexts to describe a decrease in the expression or activity of a gene, protein, or other biological component.
Example: "The study focused on the effects of stress on cellular responses, particularly the upregulation of certain genes and the downregulation of others."
Alternatives: "and the reduction of" or "and the suppression of".

Exact(60)

Upon IB-MECA treatment and the downregulation of TNF-α levels, the receptor was also downregulated.

Arthritis Research and Therapy

High level of resistance involved the mexCD-oprJ efflux pump and the downregulation of PQS quorum sensing.

Journal of Proteomics

Deep transcriptome analysis showed the activation of a set of pluripotency and germ-cell-specific markers and the downregulation of innate immune system.

Cytokine

Notably, the Egt beneficial effect was exerted through the upregulation of sirtuin 1 (SIRT1) and sirtuin 6 (SIRT6) expression and the downregulation of p66Shc and NF-κB.

Free Radical Biology and Medicine

A quantitative RT-PCR array demonstrated the upregulation of secreted frizzled-related protein (SFRP) 3 and the downregulation of SFRP4 during osteoinduction.

Biomaterials

The interaction of VRK2 proteins with JIP1 complexes and the downregulation of IL-1β signaling can have wide biological implications.

Plosone

Additionally, several studies have shown a clear correlation between miRNAs that are highly expressed in a given tissue and the downregulation of their target transcripts [6], [12], [13].

Plosone

Akt2 ablation resulted in the upregulation of p27Kip1 (p27), and the downregulation of Cdk2 and cyclin D, leading to cell cycle arrest in G0/G1.

Plosone

The relationship between iron overload and the downregulation of TBXAS1 should be clarified further.

Cancer Science

This is in line with the upregulation of Ucp2 and the downregulation of Scd1 expression.

Diabetologia

The odds ratio (OR) shows the association between ALL immunophenotype and the downregulation of HDAC7.

Cell Death and Disease

More suggestions(16)

and the depletion of

and the shrinking of

and the dwindling of

and the shrinkage of

and the palliation of

and the impairment of

and the decline of

and the reduction of

and the drop of

and the lessening of

and the fade of

and the lowering of

and the diminishing of

and the drop off of

and the name of

and the style of

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