We summarize the problem tackled here in the following way: Given a modern database application environment, how can we identify and select the database structure that provides robust performance across changing query patterns and arrival rate conditions?
The authors wish to thank the HENVINET consortium members and especially the HENVINET steering board members for their invaluable contribution to development of the framework, and reviews and comments to the database structure and functionalities.
The 2D fingerprints used for describing the reference structure and the database structures were 166-bit MDL Keys, 1052-bit BCI bit-strings, 2048-bit Daylight fingerprints, 998-bit Unity fingerprints, and 1024-bit PipECFP_4Pilot ECfingerprintsrints.
The similarity coefficients used to measure the similarity between the reference structure's fingerprint and the database structures' fingerprints were the Cosine, Forbes, Russell-Rao, Simple Match and Tanimoto coefficients [32].
The contribution of Δc3,M,0 could be reduced by modifying and expanding the flag and the database structures, in order to use a single flag to encode several sequences.
Moreover, we proposed an average-case linear time algorithm, under the assumption that the number of indels is bounded by a constant and the database structures follow the random-walk model.
Designing an individual table for each data collection enabled fast and easy modification of the database structure and the addition of new columns into the table.
Below we describe the database structure and data organization, and present new features and statistics for significantly updated RegPrecise 3.0 content.
This article reviews the scope of databases for common histopathology research projects, the ethical and legal considerations, design of the database structure, coding of data items, and import and export of data from databases.
