doi: 10.1038/sj.bjc.6600654 www.bjcancer.com © 2002 Cancer Research UK The ability of anti-oestrogens such as tamoxifen to compete with oestrogens for binding to OR and to antagonise their mitogenic action provides the basic rationale for endocrine therapy and prevention (for a review see (Osborne, 1998b) in breast cancer.
Since 1986, Japan has flaunted the international moratorium on killing whales voted by a three-quarters majority of the member nations of the International Whaling Commission (IWC), and Japan has further abused the basic rationale of scientific investigation by insisting their killing is "research," with the whale meat being sold in Japan markets in order not to "waste it".
This study was carried out within the context of the TeSLA project, though it is not an evaluation study of the effectiveness of the particular set of instruments in that project, but rather an exploration of the basic rationale of the project, and the likely value of this and other similar approaches.
Thus the basic rationale of the design and development of nanomedicines in cancer therapy is failing making it necessary to stop claiming efficacy gains via the EPR effect, while tumor targeting cannot be proved in the clinic.
The basic rationale for echocardiographic quantification and monitoring of mechanical dyssynchrony remains therefore valid.
We enthusiastically support the basic rationale for this paper and the two researched patient groups, which have been correctly balanced for most of the important prognostic factors, such as Breslow thickness, ulceration status, and tumor site.
This chapter is designed to review the basic rationale for standardized administration procedures and outlined basic WISC-IV interpretation processes.
First we introduce the basic rationale of the GeD approach and present a detailed description of GeD.
This study is an exploration of the basic rationale of the use of student authentication and authorship checking systems.
This study was an exploration of the basic rationale of the use of student authentication and authorship checking systems, and had four specific aims.
