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Pedro de Souza Rocha Simonini reported that hsa-miR-375 is overexpressed in breast cancer tumours with an ER+ status and that decreasing the expression of hsa-miR-375 will decrease the activity of ER accordingly [ 28].
All together, these results are consistent with the idea that MYC normally functions to facilitate P-TEFb's phosphorylation of the Pol II CTD on Ser2 and that decreasing the expression or activity of MYC eliminates this beneficial effect.
Our previous work suggested that the acyl-CoA synthetase ACSVL3 was overproduced in human GBM and GBM cells in culture, and that decreasing the expression of this enzyme in GBM cells reduced both their malignant behavior in culture and their tumorigenicity in nude mice [ 14].
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Because concrete is a type of porous material, water or air can permeate freely into the concrete and that decreases the durability of concrete.
One that decreases the amplitude and the initial slope of the sensillum potential, one that accelerates the repolarization phase, and one that decreases the action potential response even further than the parameters of the sensillum potential (Dolzer et al. 2003).
Results showed that TENS application decreased patients' intensity of pain and amount of analgesic requests and, related to that, decreased the incidence of side effects and increased patients' satisfaction during ESWL.
Treatment options for HNC are complicated and include surgery, radiotherapy, chemotherapy, and biological treatments that decrease the quality of life of patients with functional disabilities and facial abnormalities.
Indeed, a mutation that increases the negative charge of the CpxI accessory helix inhibits release and a mutation that decreases the negative charge enhances release.
The Webvan Group, one of the last remaining online grocers, reported a narrower-than-expected loss and announced a restructuring that decreases the cash it needs to raise this year as it seeks profitability.
Another protein, CHOP, known as GADD153 and a transcription factor that decreases the expression of Bcl-2, can also induce apoptosis [30].
The results revealed which types of ecological relationship contributed most to the system (here, exploitation) and identified the key compartments that decreased the system's degree of synergism.
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CEO of Professional Science Editing for Scientists @ prosciediting.com