Sentence examples for and subsequently boosting from inspiring English sources

In this study, the mycobacterial antigen HSP65 was used to determine whether priming cattle with a plasmid DNA vaccine and subsequently boosting with the recombinant protein in adjuvant (heterologous prime-boost approach) would result in improved and more homogenous immune responses over immunising with plasmid DNA or protein in adjuvant alone.

Thus, a number of immunisation regimens involving "priming" with DNA and subsequently "boosting" with a heterologous agent such as a different antigen delivery platform or protein with the aim of improving immunogenicity have been investigated.

Here, we demonstrate that enriching BCG with latency antigen α-crystallin and subsequently boosting the immunity in an antigen specific manner not only results in an efficient CD4 Th1 response but also imparts a significantly superior protection over the conventional BCG vaccination.

Activation of the innate immune receptor TLR3 leads to nuclear accumulation of NF-κB and IRF3 and subsequently boosts ISGs expression.

Hartosh Bal Singh, political editor of Caravan magazine, argues Modi's record, in 2002 and subsequently, boosted his appeal to a large rightwing Hindu constituency who "are not unsympathetic to the view that [Hindu] culture has not received its due and that here is a man who can stand up for Hindus and assert that they can and will rule in their country".

This steady influx of immigration in the hundreds of thousands will be needed to increase the number of people in work and subsequently boost the nation's public finances as the Government is forced to spend more on "age-related items such as pensions and healthcare", the OBR said.

To investigate the impact of various immunization regimens on the level of M.tb infection, guinea pigs were primed first i.d with BCG and subsequently boosted either intranasally (i.n) or intramuscularly (i.m) with AdAg85A vaccine (Fig. 1A).

One promising approach towards the development of potential vaccine candidate in maintaining strong and durable immunity is the "prime-boost" strategy in which immune response is primed with a plasmid DNA and subsequently boosted with either a protein Ag or with a modified viral vector expressing the same Ag [15].

The use of heterologous platforms to initially prime and subsequently boost an immune response has been shown to be effective for eliciting antibody responses [42], [43], [44], [45], [46] but is especially attractive for augmenting T cell responses [47], [48], [49], [50].

Thus, mice vaccinated first with a mixture of purified N1 and N2 proteins and subsequently boosted with the individual antigens showed a small memory response also against the heterologous subtype (40).

We determined that systemic anti-OVA antibody-mediated immune responses were induced in newborn piglets gavaged once on the day of birth with 0.5 mg or 0.05 mg OVA/CpG + MP and subsequently boosted with OVA and IFA by the i.p. route one month later.