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Furthermore, DNA damage promotes the recruitment of the DNA damage-induced kinase Chk2 to PML-NBs where it phosphorylates p53 at serine 20, thereby blocking the interaction between Mdm2 and p53, and subsequently alleviating p53 degradation [ 45].
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We first suggest a paradigm change in publishing metabolite information and subsequently explain how such change would alleviate the problems listed above.
Maternal deworming, however, does hold promise for improving the health of pregnant women in endemic areas, particularly in terms of alleviating risk of anemia and subsequently the risk of adverse pregnancy outcomes [ 18].
This problem has subsequently been alleviated by removing the monocytes prior to CD4+ T cell selection which reduces monocyte contamination from 2.9 ± 0.2% to 1.0 ± 0.1% (p = 0.0005).
Continued education and vaccination measures will help alleviate risk to companion animals, and subsequently, to humans.
Our data demonstrate that administration of gremlin siRNA plasmid to diabetic mice alleviated renal hypertrophy, cell proliferation and apoptosis, and subsequently suppressed collagen type IV accumulation and mesangial expansion, indicating beneficial effects of Gremlin inhibition on diabetic nephropathy.
It is possible that the peroxynitrite-mediated loss of MyoD, and subsequently MyHC, is partially responsible for this loss of specific tension, and so treatment with antioxidants may alleviate TNFα-induced muscle weakening by scavenging superoxide and preventing peroxynitrite formation.
Soil application of organic fertilizers is one of the good strategies to alleviate the damaging effects of Cd2+ on plants and to avoid its entry into plants (Table 1) and subsequently the food chain as shown in the present study.
We have attempted to alleviate this risk by using high stringency criteria for identification of candidate miRNAs from our aCGH data and subsequently using published NSCLC cohorts with copy number and miRNA expression data to independently validate these candidates.
In order to alleviate sampling bias, Pro-CLARA repeats the sampling and the clustering process a pre-defined number of times, q, and subsequently selects as the final clustering result the set of medoids with the maximal f (V).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com