Sentence examples for and structural constraints of from inspiring English sources

Regeneration of the damaged myocardium is one of the most challenging fronts in the field of tissue engineering due to the limited capacity of adult heart tissue to heal and to the mechanical and structural constraints of the cardiac tissue.

Our results demonstrate the role CTL responses play in shaping viral evolution, once more pointing out the importance of understanding the interaction between selective forces induced by CTL and functional and structural constraints of the virus.

Although aggregation usually cannot be completely suppressed because of the functional and structural constraints of the native fold, aggregation is reduced substantially by placing charged residues and/or β-sheet breaking residues adjacent to aggregation-prone segments [189].

Despite a strong commitment to the project by the primary care organisation's executive members, the influence resulting from the process became part of a wider diffuse network, competing with a plurality of influences and structural constraints, many of these outside the limited control of management at a local level [ 15].

The structure of the complex was determined by using NMR assignments and structural constraints and the coordinates of the CnCat crystal structure.

Stoichiometric and structural constraints allow the exclusion of one kinetic mechanism proposed for the photocycle but retain other plausible candidate kinetic mechanisms.

Considering the suggestion that the formation of structural DNA loops by interaction with the NM obeys thermodynamic and structural constraints, a further prediction of the hypothesis was that the NHOS should carry on stabilizing as a function of time even in an already post-mitotic nucleus, provided that there is any remaining DNA-structural stress to be dissipated.

Selection contributes more strongly to the size and density distributions of SSR loci derived from EST library sequence than from BAC library sequence, although all SSRs likely are subject to similar physical and structural constraints, such as slippage of DNA replication machinery, that may generate increased allelic diversity in AT-rich sequence motifs.

Artificial antibodies are largely diverse protein motifs that use the functional strategy of the antibody molecule, but aren't limited by the loop and framework structural constraints of the natural antibody.

In general, families reporting lower income and structural constraints (e.g. lack of basic services) have the lowest levels of health care access [ 36].

One of the peculiarities of gene networks is that they have an over-representation of network motifs, a signature of evolutionary and structural constraints (Milo et al., 2002; Shen-Orr et al., 2002).