The experimental design and statistical analysis were performed using Design Expert statistical software.
The ET calculations and statistical analysis were performed using the R free software (R Core Team 2012).
Clustering and statistical analysis were performed using DAnTE [38].
Normalization and statistical analysis were performed using Duke University BASE web server (https://base-server.duhs.duke.edu/).edu/
Average FRET efficiencies and statistical analysis were performed using Prism 5.0 (GraphPad software Inc., USA).
Image preprocessing and statistical analysis were performed using the Statistical Parametric Mapping software (SPM5).
Pre-processing and statistical analysis were performed using BrainVoyager 2000 and BrainVoyager QX (Brain Innovation, The Netherlands).
For the microarray data, clustering and statistical analysis were performed using SUMO and Genego (metacore) software packages.
With respect to the fMRI analyses, image pre-processing and statistical analysis were performed using the SPM5 software (www.fil.ion.ucl.ac.uk/spm).ac.uk/spm
Image preprocessing and statistical analysis were performed using Statistical Parametric Mapping (SPM5, www.fil.ion.ucl.ac.uk) which ran under MATLAB 7.2 (Math Works , Inc.
Graphical presentation, fitting and statistical analysis were performed using SigmaPlot with integrated statistical module of SigmaStat (Systat Software, Inc., San Jose, CA, USA).
