The phrase "and spread of malignant" is not complete and lacks context, but the individual words are correct and usable in written English.
It can be used in medical or scientific contexts when discussing the dissemination of malignant cells or tumors in the body.
Example: "The research focused on the mechanisms involved in the invasion and spread of malignant tumors in cancer patients."
Alternatives: "and dissemination of cancerous" or "and proliferation of malignant".
Angiogenesis is crucial in the growth and spread of malignant mammary tumors [ 38, 39].
Angiogenesis is important for the growth and spread of malignant tumours (Carmeliet, 2003).
This preliminary study demonstrates the potential feasibility of ensemble forecasting and data assimilation methods for short-term prediction of the growth and spread of malignant brain tumors.
As a result, lymphatic density (number of lymphatics per square mm bordering the melanoma) has been suggested as a prognostic indicator for the progression and spread of malignant melanoma[ 8- 11].
Furthermore, it was realized that the molecular mechanisms which limit in vitro cell proliferation in humans, among other mammals, often enhance organismal survival and function by impeding the establishment and spread of malignant tumors [ 26- 28].
Because HGF/SF was previously found in the pleural effusion fluids of patients with malignant mesothelioma and in paraffin-embedded tumour tissues, it is concluded that HGF/SF may well stimulate the growth and spread of malignant mesothelioma in vivo by paracrine and/or autocrine mechanisms.
The stroma surrounding the malignant cells is important for the growth and spread of the malignant tumour.
We consider the potential feasibility of this approach for making short-term (60-day) forecasts of the growth and spread of a malignant brain cancer (glioblastoma multiforme) in individual patient cases, where the observations are synthetic magnetic resonance images of a hypothetical tumor.
On multivariate analysis, only four retained statistical significance: inflammatory features, baseline tumour markers, number of involved nodes, and extracapsular spread of malignant cells.
This may lead to the rupture of small blood vessels in or around small undetected breast cancers, and the lethal distant spread of malignant cells.
Computed Tomography (CT) of the abdomen and pelvis after contrast administration is important both in evaluation of spread of malignant lesions and in detection of recurrence after therapy, whereas it has a limited value in primary detection and characterization of an ovarian mass.
