The phrase "and since the changes" is correct and usable in written English.
It can be used to introduce a statement that relates to changes that have occurred previously.
Example: "The project has seen significant improvements, and since the changes were implemented, productivity has increased."
Alternatives: "given the changes" or "due to the changes".
And since the changes to the marriage law 12 years ago, the number of gay couples getting married is surprisingly low.
PPV is somewhat more accurate than SPV since, under constant conditions, the SV is proportional to the pulse pressure, and since the changes in the systolic blood pressure may be influenced by some degree of transmission of airway pressure [ 16].
And since the change would not take place for decades or affect anyone near retirement age now, those who are affected will have plenty of time to prepare, Mr. Gregg said.
And since the change in density means there will be a change in mass, I can use Goce to observe the Moho".
In 1927, the entire highway was renumbered, and since this change, the trunkline has carried the M-75 moniker.
His book is a review of military craft and tactics since Napoleon, and the changes that have occurred since 1945.
The following morning, the writer met Don Enrique and talked about New York and Madrid, and the changes since Franco.
Specific genotypes will predominate during a seasonal outbreak, and since the genotypes change annually, adult reinfections occur [ 32].
He seems more passionate about the mechanics of comedy than the reality of the world, and since comedy changes less than the world does, his material reflects that.
And since the vegetable proportions change based on what you have on hand it is always a new flavor palate.
Seismic and tectonic activity have since changed the sea level and elevation of the Bodjong area of Indonesia from that during the Pliocene.
