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"This is a fundamental and significant shift in social policy," he said.
Amanda says there's been a "huge and significant shift" in the way young adults are choosing to spend and invest.
We need a sharp and significant shift in the makeup of cultural leadership in our country and the creation of a new canon of work for future generations to call their own.
We are witnessing an important and significant shift in awareness and response.
The ensuing results show that a swift and significant shift in the local energy policy of typical central European municipalities is needed.
These analyses shown in representative scatter plots in Figure 3A, indicate at a glance that TER cells displayed a dramatic and significant shift in the ratio of red-to-green differential fluorescence.
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Of course, none of these efforts will matter if organizational change, and significant shifts in how the companies are run, don't accompany them.
Saritas and Smith define discontinuities as "rapid and significant shifts in trajectories without the aspect of being mostly unanticipated or deeply surprising" which "[extend] beyond single events" and "fundamentally [alter] the previous pathways or expected direction of policies, events and planning regimes" [66].
These preparations affect more than just defense budgets and equipment purchases, and are accompanied by strengthened diplomatic relationships and significant shifts in political sentiment.
What was once a sprawling area of strawberry fields and orange groves, with a relatively homogeneous demographic, has become a county with dynamic economic growth and significant shifts in its ethnic makeup.
The most notable, and significant, shift observed in response to this question was for those who strongly agreed, 7% at baseline compared to 29% at exit (Z = −3.111, p = 0.002).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com