Sentence examples for and sequestered in a from inspiring English sources

Furthermore, our modern achievements are accessible rather than glorified and sequestered in a Louvre or a Versailles.

Upon ligand binding, cell surface EGFR is endocytosed into the cytosol and sequestered in a sorting/early endosome for either recycling or degradation [ 15].

Peptide-loaded MHC II is retained in the perinuclear area and sequestered in an enlarged peptide-loading compartment with defective trafficking of MHC II-loaded vesicles toward the periphery.

Now, when PGC-1α is deacetylated by SIRT1 and sequestered in the nucleus, a sustained effect on expression of target genes involved in the mitochondrial electron transport system is prevented.

The Rho GTPases RhoA, Rac1, and Cdc42 are posttranslationally modified by a 20-carbon geranylgeranyl lipid and are solubilized from membranes and sequestered in the cytosol in an inactive state by binding to RhoGDIs, which have a hydrophobic pocket that accommodates the geranylgeranyl group (Hoffman et al., 2000).

In the first, they are exported to the cytoplasm and sequestered in the chromatoid body (CB), a prominent and dynamic RNA-processing center in (haploid) spermiocytes that harbors a plethora of short and long RNAs including mRNAs as well as components of the RNA interference (RNAi) machinery and enzymes of the nonsense-mediated decay pathway.

HDAC5 is phosphorylated by SIK kinases and sequestered in the cytoplasm under basal conditions.

It appeared that TfR was recruited and sequestered in the perinuclear area by the optineurin foci.

Additionally, less VEGF is bound to its receptors and sequestered in the matrix following treatment.

Phosphorylated DAF-16/FoxO is subsequently exported from the nucleus and sequestered in the cytoplasm.

Foxo3a can be inactivated and sequestered in the cytoplasm by AKT activation.