Sentence examples for and sequential changes in from inspiring English sources

Together, these data confirm the fidelity of identified cell-specific cell-surface proteins and reveal the temporal and sequential changes in cell state that occur upon transcription factor mediated lineage conversion.

Prior to performing extensive genome-wide profiling of gene expression and pathway analyses in these models, we described here the validation of this approach by demonstrating the time-dependent and sequential changes in these tissues using real-time PCR and confirmation with immunohistochemical methods for genes previously demonstrated to be involved in the pathogenesis of OA.

Here, we described the validation of this approach by demonstrating the time-dependent and sequential changes in gene expression profiles of key markers for cartilage degradation, chondrocyte differentiation, vascular invasion and bone remodeling in these tissues using real-time PCR and confirmation with immunohistochemical methods.

These year-on-year and sequential changes resulted, in addition to the factors described below, from the proportionate allocation of operating expenses being impacted by the relative mix of sales and gross profit performance between Mobile Phones and Smart Devices.

Further increase of α results first in the disappearance of the links between G6P and FBP, and sequential changes do not result in 'sensible' connection topologies.

To pursue the cause of miR-143 suppression in GC cell lines, we treated MKN-1 and HSC-44PE cell lines with 0 3 μmol/L 5-aza-2′-deoxycytidine for 4 days and analyzed sequential changes in miR-143 expression by qRT-PCR.

Ewers et al. integrated the findings on changes in cortical gray matter volume, white matter fiber tracts, and brain metabolism of patients  [30], and discussed the sequential changes in neuroimaging biomarkers during different disease stages  [31], similar to the review of Lin et al. [32].

Overlapping and non-overlapping pathways and networks demonstrate the sequential changes in the course of molecular pathways in the hippocampus of ischemic mice.

The challenge for predictive toxicology is to link changes in gene and protein expression to sequential changes in phenotype, both adaptive and adverse, in a manner that is consistent with the underlying biologic mechanisms.

Early CD4−CD8− double negative (DN) thymocytes undergo a complex pattern of migration and differentiation characterized by sequential changes in expression of the cell surface markers CD25 and CD44 through the stages DN1 (CD25−CD44+), DN2 (CD25+CD44+), DN3 (CD25+CD44−), and DN4 (CD25−CD44−).

50 In humans, however, GLP-1RA use did not substantially raise calcitonin levels, and an analysis of sequential changes in calcitonin levels in several thousand diabetic subjects did not reveal a relationship between liraglutide therapy and plasma calcitonin.