In its present form there are two major limitations of this criterion; firstly it considers the strength response to be linear, and, secondly the effect of the intermediate principal stress on the strength behaviour is ignored.
Firstly, the effect of scaling the brick and mortar joints to half scale was assessed, and secondly, the effect of scaling the size of the specimen without scaling the brick and mortar size was assessed.
Two main objectives of this review were to firstly determine the effect of these programmes on levels of exercise activity, and secondly the effect of exercise on mental health and well-being.
The present study was designed to extend our knowledge, firstly, of the range of tasks and consequently the types of information for which the peptide improves consolidation processes, and secondly, the effects of AVP on information treatment processes such an information transfer.
First, we examined the expression profiles in proliferating and differentiating keratinocytes and secondly, the effects of exogenous addition of two retinoids which normally are synthesized by epidermal keratinocytes, atRA and ddRA.
Two important factors are believed to have influenced the epidemiology of RVFV, firstly, major irrigation projects and secondly, the El Niño effect.
Firstly, 11βHSD1 activity is dependent on the glucocorticoid receptor, since the co-administration of the glucocorticoid receptor antagonist RU486 blocks it; and secondly, the stimulatory effect of dexamethasone is indirect requiring new protein synthesis, since the glucocorticoid upregulation is also blocked by the protein synthesis inhibitor cycloheximide [ 13].
Secondly, the effect of age is treated as continuous and estimates have greater precision than when grouping age [ 26].
Secondly the effect RIT on GBM is interesting: it considerably prolonged DFI and overall survival relative to the untreated group.
Secondly, the effect of CTGF on trophoblast-derived HTR-8/SVneo cell adhesion and network formation was investigated.
Firstly, as angiogenesis is largely absent in the healthy adult, it was widely held that an antiangiogenic approach would be without side effects, and secondly, the fact that the endothelial cells involved in angiogenesis are normal cells meant that they did not suffer the genome instability seen in carcinoma cells and as such were unlikely to develop drug resistance.
