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Avoiding contamination is a key element of the British project so the drilling and sampling will be undertaken in conditions considered cleaner than those required in a typical surgery.
Variability from both intrinsic stochasticity and sampling will be discussed in Additional file 1.
Ultimately, the extent of restoration and sampling will be dictated by the reoccupants and building owners, and hence risk communication will be of the utmost importance.
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Based on this, a description of the study design and sample will be given, and the results of the test performance of prospective teachers at Austrian and German universities will be reported.
To ensure adequate quality and consistency of samples, centralized hands-on training will be provided and samples will be assessed on an ongoing basis.
Blood samples will be collected using standard venepuncture and phlebotomy procedures and samples will be transported to the local laboratory, where plasma/serum will be separated within 4 h of venepuncture.
You will be asked to ingest excess fat over one to three days, and samples will be collected throughout this period of time.
Purposive and theoretical sampling will be used to access participants whose data can provide depth and individual meaning.
Basal measurements including hemodynamics and blood sampling will be performed at Time 0 (T0) representing the starting point just after randomization.
A combination of random sampling and purposive sampling will be used.
Blood and urine sampling will be carried out in select centres.
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