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The Pharmaceuticals and Medical Devices Agency (PMDA) reviews the equivalence between generic and originator products from the perspective of quality, efficacy, and safety based on documents submitted by the applicants (Kuribayashi et al. 2015).
Although it is very clear that cell phone use degrades driving performance and safety based on previous studies, it is not clear whether its impacts will vary with the characteristics of drivers, such as gender, driving experience, driving behavior, and cell phone use intensity.
The Agency for Healthcare Research and Quality (AHRQ) has developed tools to measure obstetric care quality and safety based on administrative health data [ 19].
Consequently, physicians may sometimes prescribe therapies on presumptions of efficacy and safety based on clinical trial results that are not necessarily generalizable to persons of advanced age.
In Brazil, the companies need to prove the safety efficacy, quality and safety based on scientific information of phytomedicines because they are registered as drugs [ 16].
Moreover, population models may enable extrapolation of long-term efficacy and safety based on short-term pharmacokinetic and treatment response data.
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The safety of the AAD-12 protein and DAS-444Ø6-6 event was assessed for food and feed safety based on the weight of evidence and found to be as safe as non-GE soybean.
These include intensive interactive tutorials focusing on prescribing and medication safety, based on those described by Coombes and colleagues [ 26], as well as traditional mannequin-based resuscitation training and practical workshops on topics such as fluid resuscitation, fundoscopy and airway management.
Various technical aspects are studied, including damage quantification using a damage index, load rating, variation of strain energy, modal analysis, and structural safety based on simple reliability theory.
As a traditional Chinese medicine, Salvia miltiorrhiza has been shown to have reliable therapeutic effectiveness and excellent safety based on its long-term use in clinics.
Of particular interest, the Canadian school travel planning model uses a comprehensive approach where school specific interventions are developed to change travel behaviours and improve safety based on input from members of the school community (e.g., students, parents, and teachers) and other stakeholders [ 26].
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