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It is overexpressed in pre-BCR+ ALL and required for their maintenance invitro and invivo.
This systemic response was coordinated across tissues and required for tumor eradication in several immunotherapy models.
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He WT, et al. Gasdermin D is an executor of pyroptosis and required for interleukin-1beta secretion.
Moreover, most of the parameters investigated in this study and required for DEPM are actually known.
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