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The automated BIND translation process found and removed interaction entries that did not meet minimum requirements as defined by MIMIx.
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We removed interactions involving miRNAs or genes that were not present in the expression data.
The files were curated to remove interaction detection methods that were neither Y2H nor PCA, such as TAP-Tag, mass spectrometry and genetic interactions.
The weights assigned to each edge represent a valuable information to remove interaction with low informative content.
A stringent cut-off was used to remove interaction (IA) bins represented by less than 15 independent sequence counts.
The era of the "invisible radiologist" was born, with radiologists being servants of their work lists, divorced from their referrers and removed from patient interaction.
In the following step a threshold can be applied to remove interactions with low weight (and therefore low likelihood).
Ferguson, K. M. et al. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization.
ChIA-PET interactions were additionally filtered to remove interactions between regions ≤1000 bp apart.
We agree with the reviewers and removed FADD-ubiquitination data, interaction assay of FADD and LUBAC components, and FADD K0 data and the related panels.
We extract all reported physical interactions, and remove all self-interactions along with all proteins with degree >500.
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