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The review pathologists graded the tumours as well, moderately or poorly differentiated, and also assessed them using the WHO, Lauren, Mulligan and Ming classifications (Mulligan and Rember, 1954; Lauren, 1965; Ming, 1977; Watanabe et al, 1990).
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Finally, the identifiers from Matthias Mann, Rember Pieper, and Jisun Oh were pooled together to represent the urine proteome in this study.
After removing all of the redundant proteins, protein identifiers from Matthias Mann, Rember Pieper, and Jisun Oh were pooled together to generate 1607 proteins as the urine proteome in this study.
For urinary proteins with experimental MWs, 97 unique proteins were obtained from Jisun Oh, and 131 proteins were obtained from Rember Pieper, after converting their accession numbers from Swiss-Prot to IPI 3.24.
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The urinary protein identifications with experimental molecular masses were obtained from Rember Pieper et al [10] and Jisum Oh et al [11].
More than 150 proteins from Rember Pieper et al [10] and 100 proteins from Jisun Oh et al [11] were incorporated as the urine proteome with experimental MW information.
As with the anti-amyloid agents tramiprosate, tarenflurbil and bapineuzumab, the phase II trial of the anti-tangle compound Rember (methylene blue) did not meet its primary efficacy objectives [ 16].
The foundation that awarded Mr. Rember $4,000 a year to attend the University of Denver, a private institution, is careful to say the scholarship is not awarded for an individual's sexual orientation but rather for activism in the gay, lesbian, bisexual and transgender community.
"I didn't do too well in high school, academically, but being gay helped in college," Mr. Rember said.
Another drug, methylthioninium chloride (Rember), more commonly known as methylene blue (an organic dye), targets the tau protein of neurofibrillary tangles.
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