The phrase "and regulated based on" is correct and usable in written English.
You can use it when discussing how something is controlled or managed according to specific criteria or standards.
Example: "The use of pesticides in agriculture is and regulated based on environmental impact assessments."
Alternatives: "and governed by" or "and controlled according to".
In R. stricta, 29-34% of all DE genes appear circadian regulated based on homologies to Arabidopsis genes regulated by the clock (Table 2).
Genes were called significantly differentially expressed (up- or down- regulated) based on a FDR corrected p-value cut-off of 0.05.
Clones were assigned as either up or down regulated based on two conditions: a ratio of at least 1.5 fold change in at least 3 of the six replicates and also a statistical p value of < 0.05.
Occupational exposure to sucrose is only regulated based on its nuisance dust character at 5 mg/m (US Occupational Safety and Health Administration, 2010), which would lead to a daily sucrose uptake of approximately 50 mg of sucrose, which is above the daily dose of sugars reaching the smoker's respiratory tract if estimated under worst case conditions (Table 1).
Intersecting the ChIP-chip and gene expression data yielded 150 direct targets, of which 141 were grouped into 3 co-expressed gene sets (sustained up-regulated, transient up-regulated and down-regulated), based on their temporal changes in expression after TGF-β activation.
Firstly, we extracted highly expressed genes in a cell type compared with the other ones (up-regulated), and vice versa (down-regulated), based on the clustering by the original Paraclu and our pipeline, respectively.
Of the miRNAs selected for comparison, two miRNAs (miR-206 and let-7e) were up-regulated whereas two miRNAs (miR-200c and miR-27a) were down-regulated based on the results of microarray analysis.
This pattern was observed for certain genes in groups 1a, 1b, 4a, 4b, 6a and 6b, but not for those in groups 1c, 1d, 2 and 3. Some of these vicinal genes may be co-regulated, based on the microarray data [24], and these gene clusters may thus comprise operons.
Expression QTLs were declared to be significant based on a global permutation threshold of 95%% and classified as cis- or trans-regulated based on them being co-localized within the same marker interval where the respective gene model was located in the 'Nisqually-1' genome sequence.
Alternatively, are there clusters of genes that are co-regulated based on specific common properties, and whose altered expression contributes to the generation of 'epileptic neurons'?
