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During the early 1990s, second-generation modified release drug preparations achieved continuous and constant rate drug delivery, in which constant or sustained drug output minimize drug concentration "peak and valley" levels in the blood, promoting drug efficacy and reducing adverse effects [ 1, 2].
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Delivering them directly to the tumor may improve therapeutic efficacy and reduce adverse effects.
Both in vitro and in vivo studies confirmed that the ternary detachable complexes FK/p53/PEG-PLL DA) could enhance antitumor eFK/p53/PEG-PLL DAe adverse effecouldo normal cenhance
Drug delivery systems designed for enhanced drug efficacy and reduced adverse effects have evolved accompanied by the development of novel materials.
Tumor-targeted delivery of anti-cancer drugs with controlled drug release function has been recognized as a promising strategy for pursuit of increased chemotherapeutic efficacy and reduced adverse effects.
In response to stress, OsSUV3 rice plants maintained plant hormone levels that regulate the expression of several stress-induced genes and reduce adverse effects of salt on plant growth and development and therefore sustains crop productivity.
Traditional Chinese herbal medicines often consist of a combination of individual herbs to form specific formulae aimed to increase therapeutic efficacy and reduce adverse effects [2].
These potential benefits would therefore enhance the antimicrobial therapy and reduce adverse effects [ 8].
Practitioners of traditional medicine believe that combinations of herbs improve efficacy and reduce adverse effects [ 19].
It has been reported that these systems improve the efficacy of vaccine and reduce adverse effects of cytokines [ 122– 122].
The objective of doing this is to form specific formulae aimed to increase therapeutic efficiency and reduce adverse effects.
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CEO of Professional Science Editing for Scientists @ prosciediting.com