The relationship between change in each of the outcome measures (cognitive tests, plasma Aβ, CSF assays, vMRI, FDG-PET and rates of specific adverse events) and measures of drug exposure (AUC in the active treatment group) and peripheral pharmacodynamic effects (changes in plasma Aβ) were assessed using Spearman's correlation coefficient [ 15].
The apparent discrepancy between trials such as 4D or AURORA and SHARP is currently the subject of much debate within the medical community, and has centered on differences in the primary end point and rates of specific CV outcomes across the 3 trials that might explain the lack of clear benefit in the earlier trials.
Uptake and kinetic data for nutrient ions and chemically related nonnutrient analogs suggest that metabolic processes associated with root absorption of nutrients regulate both the affinity and rate of absorption of specific nonnutrient ions.
There also might be a relationship between frequency and conservation of a motif, and the frequencies of related motifs which could give some indications for the turnover (birth and death rate) of specific motifs.
This observation suggests that reemergence of this agent might be more likely to have resulted from spread of an infectious agent in immunologically naive populations and changes in the rate of specific immunity in host populations over time.
The data indicate that the maximum growth rate of specific monocultures and mixtures is higher than the average diversity effect on productivity.
Among the elderly, the IIV/LIV combination induced the same response rate of specific IgG and IgG1 as in young adults.
Various studies have exhibited different kinds of correlations between some motor, sensory, or cognitive events in a behaving animal and a variation of the firing rate of specific neurons, before, during or after this event [11, 12].
A slight but non-significant increase in the rate of specific IgG and IgM to parasite was observed in infected compared to non-infected groups.
To develop a combined condition index, both a panel rating approach and objective measurements are employed to assess surface distresses and permeability rates of specific PCP sections.
