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Nanog and Smad1 data sets also have nearly the same binding regions like Sox2 and Oct4 data sets as discussed by Chen et al. As shown in Figure 2, the significant motif found in Nanog is Oct-Sox, which means these similarity binding regions may cause Nanog motif to bind indirectly via one or both of Sox2 and Oct4 TFs and raise the difficulty to identify motifs of the TFs.
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She was on Start the Week – with Craig Raine, William Boyd and Iain McGilchrist – and raised the difficulty of generalising about evil.
There's a simple diagnostic questionnaire at the beginning and then the app will raise the difficulty level over time depending on how committed the user is to the regime.
Slowly raise the difficulty and your EC prestige will rise.
But he and his coach are absolutely clear that in future they have to change to raise the difficulty".
They all raise the difficulty of dispatching.
Some authors raise the difficulties to detect and diagnose these troubles with appropriate instruments [ 8, 7, 12, 13].
In her pink long-sleeved outfit, she looked like a prima ballerina as she performed difficult release moves and hand positions that raised the difficulty score of her routine.
One is to continue raising the difficulty and cost to Tehran of crossing the nuclear threshold.
He takes the polymetric rhythms ordinarily shared by an entire percussion section and plays them across his body — raising the difficulty of rubbing your stomach while patting your head exponentially.
After allowing me to coast through a few missions, Flashpoint raised the difficulty level.
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