Human immunodeficiency virus, HIV, hijacks the ESCRTs to burst out of the infected cells, and progressively destroys the body's immune system, which causes AIDS.
Primary biliary cirrhosis = an autoimmune disease of the liver, in which the small bile ducts are slowly and progressively destroyed.
This proliferative mass – the pannus – invades and progressively destroys articular cartilage and bone, leading to irreversible destruction of joint structure and function.
Lots of transcriptome studies show that AD can lead to the dysfunction of multiple brain regions and progressively destroys remembering, thinking, and reasoning skills [ 3].
A complex interaction of autoantibodies against the parietal cell proton pump and sensitized T cells progressively destroy the parietal cells, inducing hypochlorhydria and then achlorhydria, while autoantibodies against the intrinsic factor impair the absorption of vitamin B12.
During the progression of the clinical onset of Type 1 Diabetes (T1D), high-risk individuals exhibit multiple islet autoantibodies and high-avidity T cells which progressively destroy beta cells causing overt T1D.
The baby carried a mutant gene, inherited from its father, that makes the brain produce deformed toxic proteins that progressively destroy its cells.
This type of dementia, called multi-infarct, or vascular, dementia results from a series of small strokes that progressively destroy the brain.
Alzheimer's, like other diseases that progressively destroy our brains, disrupts our ways of being, because its earliest symptoms are a loss in our capacity to exercise a cherished ethic: autonomy.
These tumor strands are the first targets of macrophages, as the tumor strands are in close proximity to surrounding tumor stroma and are progressively destroyed [ 8].
