The phrase "and problematic to detect" is correct and usable in written English.
It can be used when discussing issues or challenges related to identifying or recognizing something, often in a technical or analytical context.
Example: "The malware was cleverly disguised, making it difficult to analyze and problematic to detect."
Alternatives: "and challenging to identify" or "and hard to recognize".
The BRCA1 gene contains multiple mononucleotide repeats, for which it is challenging to accurately detect 1 bp indels; these regions are the most problematic to detect for all current methods [ 36, 40, 41].
However, it should be noted that the greater variability of HC3 binding renders it problematic to detect small changes, so an effect on cholinergic synaptic activity cannot be ruled out.
Such small differences in FRET efficiency can be problematic when trying to detect localized signals surrounded by cytoplasm, especially in thick cells.
In this study, this could be especially problematic when trying to detect post-twinning de novo CNVs by comparing twin pairs that were genotyped on separate plates.
We present a conceptually simple and sensitive statistical method to detect deviating and potentially problematic probes in a probe set, and we assess the utility of the new method.
That Newland was using Kye to make these unreasonable demands only renders this coercive control more coercive and more controlling, and thus harder for Chloe to detect as problematic.
Consequently, χ tends to increase with N and thereby displays increasing power to detect these problematic models.
The inspection and control of such components are problematic as we need to detect small imperfections on large areas or to evaluate small differences between many semiconductor mask critical dimensions.
For example, split decomposition [ 32] with spectral analysis [ 33] has been utilized to plot split graphs to show where conflicting signal exists in a molecular data set [ 10, 34- 38], and Relative Apparent Synapomorphy Analysis (RASA [ 39, 40]) has been developed to detect problematic long branches by examining the taxon-variance plot of a molecular data set [ 41- 49].
A work cycle classification method was developed to detect anomalous and problematic situations in the work flow.
