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Overall, the burst duration and, presumably as a consequence, the burst frequency are the most fragile among the four investigated properties, indicated by smaller tolerance bars for some of the parameters.
However, birds do switch bonding partners and, presumably as a consequence, their affiliation status regularly changes across seasons and years.
We have shown in the present study that PRH directly affects nuclear retention of TLE and presumably, as a consequence, availability of TLE in discrete subnuclear domains.
Biochemical and physiological changes include replacement of the larva trilaminate outer membrane with a sphingomyelin (SM -rich double-lipid bilayer and preSM -rich as a consequence, protection by a hydrogen bond barrier before entering blood capillaries for permanent intravascular residence.
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The disassembly of focal adhesions can lead to alterations in both cell shape and motility, presumably as a consequence of reduced cell-matrix contacts 35, and it also generally coincides with the dynamic formation of podosomes/invadopodia 22, 45.
These data strongly suggest that constitutive activation of hypoxia-sensing and signaling pathways, presumably as a consequence of accumulation of reactive oxygen species [7], succinate [8] and/or another messenger molecule, underlies PGL pathogenesis.
For 15 fractions in 5 days with 6- 6- and 12 h intervals, the TCD50 was similar in CO- and air-breathing mice, presumably as a consequence of insufficient reoxygenation during the short inter-fraction intervals.
Interestingly, the biofilms appeared to be disaggregated and displayed a fibrous appearance, presumably as a consequence of cell lysis and release of intracellular components of the bacterial cells.
In mouse embryo fibroblasts, shRNA depletion of Tim produced a decrease in replication fork progression and elevated sister chromatid exchanges, presumably as a consequence of the increase in single strand DNA formation and chromatid breaks [27].
However, all contigs belonging to the human and rat sequences were assigned correctly, presumably as a consequence of having closely related reference sequences for these organisms.
Glioma cell lines vary in their sensitivity towards TRAIL, presumably as a consequence of transcriptional and epigenetic regulation of TRAIL receptors and anti-apoptotic proteins (Hawkins, 2004).
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