However, the long-term potency of current PR inhibitors as therapeutic agents is limited by the rapid development of drug-resistant variants of the PR.
However, since native Tf has a low probability of delivering its payload due to its short residence time in the cell, or low cellular association, there is room to significantly improve the potency of current systems.
Current studies underscore the functional versatility and potency of miRNAs in various aspects of the cancer phenotype, pointing to their potential clinical applications.
Current work continues to characterize the prevalence and potency of posttranscriptional regulation by RBPs (Klass et al. 2013; Ray et al. 2013).
"We talk about availability, price and potency of the drug".
How do you convey the immediacy and potency of theater?
The missile defense decision demonstrated both the awkwardness and potency of Mr. Gates's position.
Although it is premature to claim a correlation of AvrA with the clinical and epidemiological potency of Salmonellae, current studies indicate that a fine-tuning of AvrA expression takes place during the pathogenesis of Salmonella infection.
The close correlation between inhibitory potency and induction of current demonstrates that this group of compounds is unlikely to yield a non-transported inhibitor of PAT2.
Despite these advances, intracellular targets remain difficult to perturb using exogenous proteins; even modest success can require high concentrations of exogenous protein because of the limited potency of most current methods.
