Sentence examples for and potency in a from inspiring English sources

Network representations visualize the distribution of 2D similarity relationships and potency in a data set and give an overview of global and local features of an activity landscape.

X-ray crystallographic data of the lead molecule with p38 were used to design analogues with improved binding affinity and potency in a cell assay of LPS-induced TNFα production.

A fusion protein between a single-chain antibody and a bacterial toxin is currently being tested for local treatment of head and neck tumours in a phase I trial (Quenneville et al, 2005), and has shown extraordinary antitumour activity and potency in a xenograft model (Di Paolo et al, 2003).

These phenomena are as important as pharmacological effect and potency in designing a "drug-like" molecule.

He wanted quality in midfield to replace the departing Frank Lampard and potency in attack after a failure of his strikers last season sabotaged his attempts to reclaim the Premier League.

Seismic moment and potency in each structure are slightly smaller than those obtained in the combined inversion.

Anti-V3 mAbs exhibited the most breadth and potency in neutralizing the evolving viruses.

In a preliminary report for 25 compounds belonging to different chemical classes, a correlation coefficient of 0.36 was found between carcinogenic potency in small rodents and potency in autoradiographic repair.

Before characterizing GC transcript responses in TM cells, we deemed it important to directly measure and compare the GR binding affinity for DEX, FA, and TA, and their potency in a GR-mediated transactivation assay.

An optimization of the para-substituent of the 8-phenyl ring of 9-OH-9-deazaxanthines led to the discovery of compound 38, which exhibited outstanding hA2B affinity (Ki = 1.0 nM), good selectivity over hA2A, hA1 and hA3 (selectivity indices = 100, 79 and 1290, respectively) and excellent antagonist potency in a functional assay on rat A2B (pA2B = 9.33).

Moreover, RB200 inhibited EGF-stimulated and NRG1-β1-stimulated tyrosine phosphorylation of HER family proteins (HER1, HER2 and HER3) in vitro and has shown potency in a variety of cell proliferation assays [ 18].