The phrase "and persistent decrease in" is correct and usable in written English.
It can be used when discussing a continuous reduction in a particular variable or measurement over time.
Example: "The study revealed a significant and persistent decrease in air quality levels over the past decade."
Alternatives: "and ongoing decline in" or "and continual reduction in".
Exercise-induced arterial hypoxemia was defined as a progressive and persistent decrease in SaO2 during exercise and a drop between resting and the end of the exercise of more than 4%[2026, 26].
Exercise-induced arterial hypoxemia was defined as a progressive and persistent decrease in SaO2 during exercise and a drop of more than 4%% between resting levels and final levels after exercise had ceased [20, 26].
Long-term data from the PKUDOS registry suggest that sapropterin has a tolerable safety profile and that continuous use is associated with a significant and persistent decrease in blood Phe and improvements in dietary Phe tolerance.
However, LPS sheep presented an early severe and persistent decrease in lactate clearance (C: 575 vs 1188 and D: 907 vs 1410 ml/kg/h), fig 3 Figure 3. Hyperdynamic endotoxic shock induces an early, severe and persistent impaired lactate clearance that is not related to liver hypoerfusion, O2 extraction or mitochondrial function.
Transfection of BECN1, ATG5, ULK1, and ATG7 shRNA led to a significant and persistent decrease in mRNA and protein level at 48 h post-transfection (Fig. 2A).
By contrast, we saw a rapid and persistent decrease in GFP-Ets-1 protein level, suggesting enhanced Ets-1 protein degradation.
When the sociologists Sheela Kennedy and Frank Furstenberg studied marriage and divorce, they found that for people who had been in the highest-quality marriages, divorce produced very large and persistent decreases in overall happiness.
Similar challenges with ET produced rapid hypotension associated with sharp and persistent decreases in central venous pressure and systemic vascular resistance.
We found that AgRP neurons responded with rapid and persistent decreases in activity to both a food-predicting cue (lickspout placement near the snout) and to feeding onset, and that such decreases were sustained at later periods (e.g., 15 45 min post-feeding onset).
Other preclinical studies previously suggested that preincubation of colon carcinoma cells with IRI before FU enhances the incorporation of FU derivatives into the DNA and DNA protein complexes with a parallel and more persistent decrease in TS activity (Guichard et al, 1998).
The long-term effect of infliximab at 1 year was recently described in a small population of patients with RA (n = 26) [ 9], manifesting as a persistent increase in osteocalcin (reflecting bone formation) and a persistent decrease in CTX-I (reflecting bone resorption).
