Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting and persistent consequence of numerous classes of antineoplastic agents, affecting up to 30%40%% of patients.
The rationale for examining long-term effects in the present was based on the dearth of information available in the persistent consequences of mTBI.
(One persistent consequence of his schemes was that they seemed promising at first, but left workers too exhausted to function consistently over the long term).
Together, these results suggest that neuroinflammation can endure weeks after injury but housing rats in EE during recovery can modulate this persistent consequence of mTBI.
Our results demonstrate both immediate and persistent energetic consequences of gene copy number in a multicellular organism.
The result of a yearlong study, this report documents the situation before the storm, the immediate impact of Katrina and its persistent consequences, including a dramatically understaffed police force, insufficient jail space, and inadequate legal representation for indigent defendants.
The developmental programming hypothesis proposes that adverse influences during critical periods in development permanently alter tissue structure and function, which may have persistent consequences for the long-term health of the offspring [ 1].
Because the duration of perceived risk in HCWs after the resolution of SARS is correlated with the severity of outcome, identifying and supporting HCWs who are at the highest risk for multiple and persistent psychological and occupational consequences of an outbreak may be possible by identifying HCWs whose perceived risk has not returned to normal within a few months after the event.
"Cancer can be considered a chronic disease, in part because of the serious consequences and persistent nature of some of cancer's late effects," the committee said.
Persistent neurobehavioral consequences of chlorpyrifos exposure in zebrafish have also been demonstrated (Eddins et al. 2010; Levin et al. 2003).
By defining the principal events mediating epigenomic changes it is anticipated that novel approaches will be developed to inhibit, attenuate or reverse the persistent deleterious consequences of seizures in the epileptic brain.
